Description
What are Tadalafil 2.5mg-80mg Tablets – Generic Cialis
Tadalafil tablets 2.5mg – 80mg acts on the erectile tissue of the penis to increase blood flow to cause an erection. During sexual stimulation nitric oxide is released in the erectile tissue of the penis which activates the enzyme guanylate cyclase. This enzyme increases levels of a chemical called cyclic guanosine monophosphate (cGMP), which relaxes the blood vessels in the penis and allows blood to fill the spongy erectile tissues to cause an erection. Another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP preventing blood flow into the penis, which causes loss of an erection. Tadacip 20 inhibits the action of PDE5 which resolves erectile dysfunction by allowing the natural process of sexual stimulation to activate the cGMP mechanism for achieving and maintaining an erection.
How does Tadalafil 2.5mg-80mg work?
Like the drugs Sildenafil and Vilitra, Tadalafil works as a phosphodiesterase type 5 inhibitor (PDE5 inhibitor) which blocks the degradative action of cGMP-specific PDE5 on cGMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum (which is sponge-like erectile tissue that holds most of the blood during an erection) of the penis.
How long does Tadalafil 2.5mg-80mg last?
The maximum recommended dosing frequency is once per day. Tadalafil may be taken between 30 minutes and 36 hours prior to anticipated sexual activity. Patients may initiate sexual activity at varying time points relative to dosing in order to determine their own optimal window of responsiveness.
Tadalafil is approximately 80% bioavailable and has the slowest absorption of all available PDE5 inhibitors and may take up to 2 hours to reach its maximum effectiveness. Another benefit of Tadalafil is the longer half-life, which helps to combat performance anxiety that stems from the short half-life of other ED treatments. Other uses for Tadalafil is for the treatment of benign enlargement of the prostate and pulmonary arterial hypertension.
Treating erectile dysfunction (impotence) with Tadalafil 2.5mg-80mg
Tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor, used to treat erectile dysfunction in men (impotence). During sexual stimulation nitric oxide is released in the erectile tissue of the penis (corpus cavernosum), and activates the enzyme guanylate cyclize. This increases levels of a chemical called cyclic guanosine monophosphate (cGMP) that relaxes the blood vessels in the penis and allows blood to fill the spongy erectile tissues to cause an erection. Another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP preventing blood flow into the penis, which causes loss of an erection. When taken before planned sexual activity, Tadalafil inhibits PDE5 allowing cGMP to continue to increase blood flow into the penis causing an erection.
What are the side effects of Tadalafil, Cialis Generic?
The most commonly reported side effects when taking Tadalafil include: headache, dizziness or light-headedness, flushing, nasal congestion, dyspepsia (heartburn), nausea. Less common side effects include, visual disturbance, increased tear formation causing watery eyes, changes in blood pressure (hypo and hypertension), sleepiness, dyspnoea (shortness of breath), pain (in the back joints, abdomen).
When should Tadalafil not be used?
- You should not use Tadalafil if you:
- Are allergic to tadalafil or any ingredient of a particular product
- Are taking any nitrate medication, such as nitroglycerin for angina, as it may lead to a severe drop in blood pressure
- Have liver or kidney disease
- Have a condition where sexual intercourse inadvisable due to cardiovascular or heart problems or you have had a heart attack or stroke in the last 6 months
- Have abnormally high or low blood pressure
- Have an eye disease like non-arteritic anterior ischaemic optic neuropathy (NAION), which causes loss of vision, or if you have retinitis pigmentosa
- Drink large amounts of alcohol or grapefruit juice
- Are taking medication that may interact with Tadalafil or may increase your risk for side-effects, antibiotics like erythromycin and rifampicin, drugs for high blood pressure, ritonavir or saquinavir (for HIV), antifungals like itraconazole or ketoconazole, non-selective alpha-blockers like doxazosin for high blood pressure, tamsulosin and prazosin for enlarged prostate, antacids , nitrates such as glyceryl trinitrate for angina and other heart conditions
What medications interact with Tadalafil?
Several medications interact with Tadalafil and should either not be taken while you are taking Tadalafil or only after discussion and instruction from your doctor:
- Drugs that cause a serious reaction with Tadalafil: any nitrate medication, such as nitroglycerin for angina
- Drugs that affect Tadalafil: antibiotics like erythromycin and rifampicin, antifungals like itraconazole or ketoconazole, antacids, ritonavir or saquinavir for HIV
- Drugs that are affected by Tadalafil: non-selective alpha-blockers like doxazosin for high blood pressure, tamsulosin and prazosin for enlarged prostate, nitrates such as glyceryl trinitrate for angina and other heart conditions, drugs for high blood pressure (may need dose adjustment)
How should Tadalafil be taken?
The maximum recommended dose of Tadalafil is 20 mg, taken prior to anticipated sexual activity. The maximum recommended dosing frequency is once per day. Tadacip may be taken between 30 minutes and 36 hours prior to anticipated sexual activity. Patients may initiate sexual activity at varying time points relative to dosing in order to determine their own optimal window of responsiveness. The dose may be lowered to 10 mg based on individual response and tolerability. Tadalafil may be taken without regard to food.
